ROM Plus Rupture of Membranes

ROM Plus Rupture of Membranes

Best in class sensitivity delivered conveniently and cost effectively.


ROM Plus is unique in that it detects both Alpha-fetoprotein (AFP)
and IGFBP-1 (pp12) using a monoclonal/polyclonal antibody approach-improving its sensitivity.

Timely and accurate diagnosis of PROM allows for gestational age-specific interventions designed to minimize the potential risk of complications to both mother and baby.


Dual Protein Markers: Placental Protein-12 & Alpha-fetoprotein


  • PP12 is detected early in first trimester and “plateaus” throughout the duration of the pregnancy
  • AFP is detected at the end of the 2nd trimester/beginning of the 3rd trimester (< 37 weeks)where full confidence is required in the accurate diagnosis
  • AmniSure and Actim PROM tests only employ one protein marker

Polyclonal and Monoclonal Antibody Approach


  • Reduces the chance of false negatives
  • Provides a better ‘screening’ method to detect the presence of protein markers
  • Improves the opportunity for denatured protein detection
  • AmniSure and Actim PROM tests only employ a monoclonal antibody approach


Ease of Use:


  • 15 second sample collection
  • 15 second mix within buffer solution
  • Spill resistant vial to avoid accidental spilling of buffer solution and/or sample
  • Easy to use test cassette with built in time


Product Literature

Clinical Studies


Product Literature

ROMplus Brochure

Clinical Studies

Actim™ Prom, AmniSure® and ROMplus® – A Comparitive Study

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